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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITPR3 All Species: 5.15
Human Site: S1839 Identified Species: 14.17
UniProt: Q14573 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14573 NP_002215.2 2671 304106 S1839 S F S I P G S S S R Y S L G P
Chimpanzee Pan troglodytes XP_518409 2650 301859 S1834 X R R G H E V S E R V Q S S E
Rhesus Macaque Macaca mulatta XP_001102937 2700 308048 K1859 R D S T L H L K E G M K G Q L
Dog Lupus familis XP_538867 2647 301264 P1815 S F S M P G S P S R Y S L G P
Cat Felis silvestris
Mouse Mus musculus P70227 2670 304256 S1839 S F S M P S S S R Y L L G L G
Rat Rattus norvegicus Q63269 2670 304268 S1839 S F S M P S S S R Y S L G P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418035 2664 304757 P1836 T F M M P G T P S R Y P L A L
Frog Xenopus laevis NP_001084015 2693 306654 T1854 R E P S G Q I T E E A K E Q L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29993 2838 319089 G1973 K H G L K S N G V V I T E E L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.8 65.2 95.7 N.A. 95.3 95.2 N.A. N.A. 89.7 62.9 N.A. N.A. 51.7 N.A. N.A. N.A.
Protein Similarity: 100 97.3 77.8 97 N.A. 97.6 97.4 N.A. N.A. 94.5 77.6 N.A. N.A. 68.1 N.A. N.A. N.A.
P-Site Identity: 100 13.3 6.6 86.6 N.A. 40 40 N.A. N.A. 46.6 0 N.A. N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 13.3 6.6 93.3 N.A. 46.6 46.6 N.A. N.A. 66.6 6.6 N.A. N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 12 0 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 12 0 0 0 12 0 0 34 12 0 0 23 12 12 % E
% Phe: 0 56 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 12 12 12 34 0 12 0 12 0 0 34 23 23 % G
% His: 0 12 0 0 12 12 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 12 0 0 12 0 0 0 12 0 0 0 0 % I
% Lys: 12 0 0 0 12 0 0 12 0 0 0 23 0 0 0 % K
% Leu: 0 0 0 12 12 0 12 0 0 0 12 23 34 12 45 % L
% Met: 0 0 12 45 0 0 0 0 0 0 12 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 12 0 56 0 0 23 0 0 0 12 0 12 23 % P
% Gln: 0 0 0 0 0 12 0 0 0 0 0 12 0 23 0 % Q
% Arg: 23 12 12 0 0 0 0 0 23 45 0 0 0 0 0 % R
% Ser: 45 0 56 12 0 34 45 45 34 0 12 23 12 12 0 % S
% Thr: 12 0 0 12 0 0 12 12 0 0 0 12 0 0 0 % T
% Val: 0 0 0 0 0 0 12 0 12 12 12 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 23 34 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _